CGT is an advanced carrier genetic test, which determines whether a couple are carriers of genetic mutations that could be transmitted to their children.
CGT uses Next-Generation Sequencing (NGS) to analyse a wide panel of disorders including as Cystic Fibrosis, Spinal Muscular Atrophy, Fragile-X Syndrome.
Uses NGS to analyse 6,600 pathogenic mutations across 547 genes linked to more than 600 genetic disorders. It is the most complete panel currently available.
Uses NGS to analyse 3,500 pathogenic mutations across 250 genes mutations associated with the most prevalent diseases.
Recommended in cases where the person has a family history and believes they carry a mutation in a specific gene. CGT One uses NGS to sequence the entire gene or a panel of genes linked to the disease in order to locate the existing mutations.
Most carriers of genetic mutations don’t have a family history of these disorders.
Pros and cons of implementing a carrier genetic test in an infertility practice. Gil-Arribas E et al. Curr Opin Obstet Gynecol. (2016)
Comprehensive carrier genetic test using next-generation deoxyribonucleic acid sequencing in infertile couples wishing to conceive through assisted reproductive technology. Martin J et al. Fertil Steril. (2015)
Genetic Carrier Screening in the Twenty-first Century. Yao R et al. Clin Lab Med. (2016)
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