The POC test analyzes fetal tissues from a miscarriage to determine if the lost pregnancy was the result of a chromosomal aneuploidy.
This test can provide you an important information about the possible causes of your patient’s miscarriage to help them to plan any future pregnancy..
The genetic study of fetal tissue is a valuable tool to determine the cause of the miscarriage, which enables appropriate reproductive counseling for the couple.
POC is recommended for all couples who have suffered a miscarriage, but is essential for couples who have experienced recurring spontaneous abortions and those undergoing assisted reproduction treatments.
This technique does not detect balanced structural chromosomal abnormalities and may not detect: low-level mosaic aneuploidy, triploid/tetraploid chromosomes, uniparental disomy, deletions or duplications under 10 Mb.
Campos-Galindo I, et al. J Assist Reprod Genet 2012; 32:839-48
Martínez MC, et al. Fertil Steril 2010;93:289-92.
