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Genetic Solutions > EndomeTRIO

EndomeTRIO: The endometrium matters

A new dimension of endometrial health to improve the reproductive prognosis of your patients.

  • Technical Overview
  • Documentation
  • Scientific evidence
  • I’m not a health specialist

EMMA + ALICE + ERA

A better understanding of endometrial health to improve reproductive prognoses

30% of infertile women
have pathogenic bacteria

Are you interested?

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Or Email us at info.me@igenomix.com

Overview

  • EndomeTRIO
  • Benefits
  • Indications

What test does the EndomeTRIO analysis include?

Endometrial Receptivity Analysis

The ERA test evaluates the stage of an endometrium to determine if a receptive or non-receptive genetic profile is present at the time of biopsy.

Endometrial Microbiome Metagenomic Analysis

A screening test to evaluate the endometrium at the microbiological level.

Analysis of Infectious Chronic Endometritis

ALICE detects the bacteria causing chronic endometritis to improve your patient’s reproductive prognosis.

What is the procedure?

Why does the endometrium matter?

  • The endometrium has been noted as a key factor for a healthy pregnancy in recent scientific studies.
  • Since 2011, Igenomix has been conducting a deep line of research to understand the role of the endometrial factor in recurrent implantation failure patients.
  • Our recent publications in the American Journal of Obstetrics and Gynecology (AJOG) demonstrate a new dimension of endometrial health that can improve your patient’s reproductive prognosis.

Why use EndomeTRIO test?

  • A better understanding of endometrial health to improve your patient’s reproductive prognosis: Analyses Endometrial receptivity, chronic endometritis and endometrial flora.
  • EndomeTRIO uses the latest Next Generation Sequencing technology.

Who should use EndomeTRIO Analysis?

  • Women who have experienced implantation failure with morphologically good quality embryos
  • Women with a history of recurrent pregnancy loss
  • Women who have an atrophic endometrium (< 6mm) present higher risk of having a displaced WOI.
  • Women with Chronic Endometritis

ERA Test limitations

  • There is a risk (<5%) to get a non-informative result, in which the biopsy procedure has failed to obtain a sufficient quantity and/or quality of tissue to be able to make a diagnosis. If this should occur a new biopsy will be required.
  • Pregnancy is not guaranteed, even with a receptive result. Poor embryo quality, genetic abnormalities, or previous pathologies can also reduce the likelihood of becoming pregnant.
  • The ERA® does not test for any other endometrial pathology and does not asses or provide a prediction for the health of a subsequent pregnancy.

EMMA/ALICE Limitations

  • These tests are not able to detect resistance to antibiotics.
  • ALICE only detects the presence of pathogens associated with chronic endometritis.
  • A negative result does not rule out the presence of other endometrial pathogens.
  • The tests are not 100% accurate at determining the bacterial species.
  • Specialists’ documents

Clinical Sheets

Download

Brochure

Download

Manual

Download

Scientific evidence

Relevant related studies:

Cicinelli et al. Reprod Sci 2014; 21(5):640-7.

Cicinelli et al. Hum Reprod. 2015; 30(2):323-30. 

Moreno I. et tal. Am J Obstet Gynecol, 2018, 218(6):602-602.

Moreno I. et tal. Am J Obstet Gynecol. 2016;215(6):684-703.

If you´re a little lost with this technical information...

Can we help you?

I’m not a health specialist

Igenomix and fertility

We work to make a world in which infertility is no longer an impossible barrier. Together with clinics and fertility doctors worldwide we investigate human reproduction to change the lives of couples who are trying to conceive.

Learn more about Igenomix

Other services

ERA

Evaluates the endometrial receptivity

More Information

EMMA

Evaluates the endometrium at the microbiological level

More information

ALICE

Detects the bacteria causing chronic endometritis

More information

Igenomix is in the media

IGENOMIX has not affiliated any news outlet or publication identified above. News coverage does not constitute an endorsement of IGENOMIX or its products
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يستخدم هذا الموقع ملفات تعريف الارتباط لتحسين تجربتك أثناء التنقل عبر الموقع. من بين ملفات تعريف الارتباط هذه ، يتم تخزين ملفات تعريف الارتباط المصنفة حسب الضرورة على متصفحك لأنها ضرورية لعمل الوظائف الأساسية للموقع. نستخدم أيضًا ملفات تعريف الارتباط الخاصة بطرف ثالث والتي تساعدنا في تحليل وفهم كيفية استخدامك لهذا الموقع. سيتم تخزين ملفات تعريف الارتباط هذه في متصفحك فقط بموافقتك. لديك أيضًا خيار إلغاء الاشتراك في ملفات تعريف الارتباط هذه. لكن إلغاء الاشتراك في بعض ملفات تعريف الارتباط هذه قد يكون له تأثير على تجربة التصفح لديك.
Necessary
Always Enabled
أي ملفات تعريف ارتباط قد لا تكون ضرورية بشكل خاص لكي يعمل موقع الويب ويتم استخدامها خصيصًا لجمع بيانات المستخدم الشخصية عبر التحليلات والإعلانات والمحتويات الأخرى المضمنة تسمى ملفات تعريف ارتباط غير ضرورية. من الضروري الحصول على موافقة المستخدم قبل تشغيل ملفات تعريف الارتباط هذه على موقع الويب الخاص بك.
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أي ملفات تعريف ارتباط قد لا تكون ضرورية بشكل خاص لكي يعمل موقع الويب ويتم استخدامها خصيصًا لجمع بيانات المستخدم الشخصية عبر التحليلات والإعلانات والمحتويات الأخرى المضمنة تسمى ملفات تعريف ارتباط غير ضرورية. من الضروري الحصول على موافقة المستخدم قبل تشغيل ملفات تعريف الارتباط هذه على موقع الويب الخاص بك.
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